Established BMI-associated genetic variants and their prospective associations with BMI and other cardiometabolic traits: the GLACIER Study
نویسندگان
چکیده
منابع مشابه
Shifts in BMI category and associated cardiometabolic risk: prospective results from HEALTHY study.
OBJECTIVES To evaluate shifts across BMI categories and associated changes in cardiometabolic risk factors over 2.5 years in an ethnically diverse middle school sample. METHODS As part of HEALTHY, a multisite school-based study designed to mitigate risk for type 2 diabetes, 3993 children participated in health screenings at the start of sixth and end of eighth grades. Assessments included ant...
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Multiple genetic loci have been associated with body mass index (BMI) and obesity. The aim of this study was to investigate the effects of established adult BMI and childhood obesity loci in a Greek adolescent cohort. For this purpose, 34 variants were selected for investigation in 707 (55.9% females) adolescents of Greek origin aged 13.42 ± 0.88 years. Cumulative effects of variants were asses...
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It has been suggested that mitochondrial dysfunction plays a role in metabolic disorders including obesity, diabetes, and hypertension. The fact that mitochondrial defects can be accumulated over time as a normal part of aging may explain why some individuals can eat all sorts of foods and remain at normal weight while they are young. However, around the fourth decade of life there is a trend t...
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OBJECTIVE This study examined whether change in body mass index (BMI) or waist circumference (WC) is associated with change in cardiometabolic risk factors and differences between cardiovascular disease specific and diabetes specific risk factors among adolescents. We also sought to examine any differences by gender or baseline body mass status. DESIGN The article is a longitudinal analysis o...
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ژورنال
عنوان ژورنال: International Journal of Obesity
سال: 2016
ISSN: 0307-0565,1476-5497
DOI: 10.1038/ijo.2016.72